MIxT identifies links between molecular processes in breast cancer tumors and blood cells.
(Image by Vanessa Dumeaux CC-BY)
Researchers have developed a new software tool that examines various gene expressions in different body tissues. Using this tool, they found an association between breast cancer tumor cells and immune system cells in the bloodstream. In particular, researchers found that molecular processes vary with subtypes: for example, immune system-suppressing processes operating in conjunction with certain breast cancer subtypes, including the basal breast cancer subtype. This research can help scientists gain a broader understanding of how our bodies and immune system respond to the challenges of the presence of a particular tumor.
Authors:
Vanessa Dumeaux , Bjørn Fjukstad, Hans E. Fjosne, Jan-Ole Frantzen, Marit Muri Holmen, Enno Rodegerdts, Ellen Schlichting, Anne-Lise Børresen-Dale, Lars Ailo Bongo, Eiliv Lund , Michael Hallett
Corresponding author:
Vanessa Dumeaux, Computational Biology, Concordia, Montreal, QC, Email: vanessadumeaux@gmail.com
Original paper published in PLOS Computational Biology on September 28, 2017.
