{"id":777,"date":"2014-03-30T13:15:47","date_gmt":"2014-03-30T18:15:47","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=777"},"modified":"2014-04-03T11:51:19","modified_gmt":"2014-04-03T16:51:19","slug":"le-gene-de-la-salive-associe-a-lobesite","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/le-gene-de-la-salive-associe-a-lobesite\/","title":{"rendered":"Le g\u00e8ne de la salive associ\u00e9 \u00e0 l’ob\u00e9sit\u00e9"},"content":{"rendered":"
\"Plus<\/a>

Plus de 50 pour cent des Canadiens sont ob\u00e8ses ou en surcharge pond\u00e9rale. (Cr\u00e9dit photo: Gaulsstin, flickr.com<\/a>)<\/p><\/div>\n

Une personne qui poss\u00e8de un grand nombre de copies d\u2019un g\u00e8ne augmente la quantit\u00e9 de prot\u00e9ines produites associ\u00e9es \u00e0 ce g\u00e8ne. Une nouvelle \u00e9tude en g\u00e9nomique men\u00e9e aupr\u00e8s de 6 200 personnes montre un lien entre un faible nombre de copies du g\u00e8ne de l\u2019amylase, une enzyme pr\u00e9sente dans la salive qui nous permet de briser l\u2019amidon en sucre digestible, et l\u2019ob\u00e9sit\u00e9 et un indice de masse corporelle (IMC) \u00e9lev\u00e9. Les gens avec les plus faible nombres de copies du g\u00e8ne de l\u2019amylase ont 8 fois plus de risque d\u2019\u00eatre ob\u00e8se que les gens avec un nombre \u00e9lev\u00e9 de copies du g\u00e8ne. Cette \u00e9tude ouvre la voie \u00e0 de nouveaux traitements contre l\u2019ob\u00e9sit\u00e9 fond\u00e9s sur les concentrations d\u2019enzymes digestives.<\/p>\n

<\/p>\n

Pour lire l\u2019article original publi\u00e9 dans\u00a0Nature Genetics<\/em>\u00a0le 3<\/strong>0 mars 2014<\/strong>,\u00a0cliquez\u00a0ici<\/span>.<\/a><\/p>\n

Auteur \u00e0 contacter pour plus d\u2019informations<\/strong><\/span><\/p>\n

Philippe Froguel<\/a>, Coll\u00e8ge imp\u00e9riale de Londres<\/h4>\n

Robert Sladek<\/a>, Universit\u00e9 McGill<\/h4>\n","protected":false},"excerpt":{"rendered":"

Une personne qui poss\u00e8de un grand nombre de copies d\u2019un g\u00e8ne augmente la quantit\u00e9 de prot\u00e9ines produites associ\u00e9es \u00e0 ce g\u00e8ne. Une nouvelle \u00e9tude en g\u00e9nomique men\u00e9e aupr\u00e8s de 6 200 personnes montre un lien entre un faible nombre de copies du g\u00e8ne de l\u2019amylase, une enzyme pr\u00e9sente dans la salive qui nous permet de […]<\/p>\n","protected":false},"author":3,"featured_media":775,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[531],"tags":[910,694,695,55],"class_list":["post-777","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-paper-of-interest-fr","tag-genetique","tag-medecine","tag-sante","tag-sante-publique"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/04\/7612551654_a9eea22ea6.jpg","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-cx","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=777"}],"version-history":[{"count":2,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/777\/revisions"}],"predecessor-version":[{"id":780,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/777\/revisions\/780"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/775"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=777"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}