![](\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\"){kind=icon}
"},"content":{"rendered":"JAMA<\/em><\/a> JAMA Published\u00a0December 18, 2018 11:00 ET (News releases from JAMA and McMaster University) This study\u00a0combined the results of 96 randomized clinical trials with about 26,000 participants to compare opioids with placebo and non-opioid alternative pain medications for the treatment of chronic non-cancer pain. Opioids were associated with small improvements in pain and physical functioning but […]<\/p>\n","protected":false},"author":1,"featured_media":4853,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1327,25],"tags":[],"class_list":["post-6550","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article-scientifique","category-paper-of-interest"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2016\/05\/14329622976_2ae10f5741_z.jpg","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-1HE","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/6550","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=6550"}],"version-history":[{"count":1,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/6550\/revisions"}],"predecessor-version":[{"id":6553,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/6550\/revisions\/6553"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/4853"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=6550"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=6550"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=6550"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nPublished\u00a0December 18, 2018 11:00 ET<\/strong> (News releases from JAMA<\/em><\/a> and McMaster University<\/a>)
\nThis study\u00a0combined the results of 96 randomized clinical trials with about 26,000 participants to compare opioids with placebo and non-opioid alternative pain medications for the treatment of chronic non-cancer pain. Opioids were associated with small improvements in pain and physical functioning but increased risk of vomiting compared with the placebo. The comparisons of opioids with non-opioid pain medication alternatives suggests the benefit for pain and functioning may be similar; however, the quality of evidence from the studies wasn\u2019t high. None of the reported studies documented rates of addiction.
\nSummary video<\/strong><\/a>
\nLead author:\u00a0<\/strong>Jason Busse, McMaster University – bussejw@mcmaster.ca
\n<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"