{"id":5331,"date":"2017-02-08T11:06:32","date_gmt":"2017-02-08T16:06:32","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=5331"},"modified":"2017-02-08T11:06:32","modified_gmt":"2017-02-08T16:06:32","slug":"a-small-percentage-of-genes-determine-much-of-our-height","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/a-small-percentage-of-genes-determine-much-of-our-height\/","title":{"rendered":"A small percentage of genes determine much of our height <img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<p>How tall we are is largely determined by our genetic makeup, and much of that is inherited. But a recent study reveals that there are 80 genetic variants (alleles) that occur at lower frequency, but have a significant effect on the individual&#8217;s height &#8211; up to 2 centimetres of height per allele, which is ten times greater than the average effect of common genes. Alleles are essential to study of rare genetic disorders or complex diseases. This discovery can help develop early diagnoses for these disorders.<\/p>\n<p><strong>Authors:<\/strong><\/p>\n<p>Eirini Marouli, Mariaelisa Graff, Carolina Medina-Gomez, Ken Sin Lo, Andrew R. Wood, Troels R. Kjaer, Rebecca S. Fine, Yingchang Lu, Claudia Schurmann, Heather M. Highland, Sina R\u00fceger, Gudmar Thorleifsson, Anne E. Justice, David Lamparter, Kathleen E. Stirrups, Val\u00e9rie Turcot, Kristin L. Young, Thomas W. Winkler, T\u00f5nu Esko, Tugce Karaderi, Adam E. Locke, Nicholas G. D. Masca, Maggie C. Y. Ng, Poorva Mudgal, Manuel A. Rivas, <a href=\"http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/full\/nature21039.html\" target=\"_blank\">et al.<\/a><\/p>\n<p><strong>Corresponding author:<\/strong><\/p>\n<p>Guillaume Lettre, Universit\u00e9 de Montr\u00e9al, Email: <a href=\"mailto:guillaume.lettre@mhi-humangenetics.org\" target=\"_blank\">guillaume.lettre@mhi-<wbr \/>humangenetics.org<\/a>; Tel: <a href=\"tel:(514)%20376-3330\" target=\"_blank\">+1 514 376 3330<\/a><\/p>\n<p><a href=\"http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/full\/nature21039.html\" target=\"_blank\">Original paper<\/a> published in <em>Nature<\/em> on February 1, 2017.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>How tall we are is largely determined by our genetic makeup, and much of that is inherited. But a recent study reveals that there are 80 genetic variants (alleles) that occur at lower frequency, but have a significant effect on the individual&#8217;s height &#8211; up to 2 centimetres of height per allele, which is ten [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[909],"class_list":["post-5331","post","type-post","status-publish","format-standard","hentry","category-paper-of-interest","tag-genetics"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-1nZ","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/5331","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=5331"}],"version-history":[{"count":1,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/5331\/revisions"}],"predecessor-version":[{"id":5332,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/5331\/revisions\/5332"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=5331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=5331"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=5331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}