{"id":4019,"date":"2015-04-05T14:07:24","date_gmt":"2015-04-05T19:07:24","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=4019"},"modified":"2015-04-06T14:07:36","modified_gmt":"2015-04-06T19:07:36","slug":"damaged-tau-is-the-main-cause-behind-alzheimers-disease","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/damaged-tau-is-the-main-cause-behind-alzheimers-disease\/","title":{"rendered":"Damaged tau is the main cause behind Alzheimer\u2019s disease"},"content":{"rendered":"<p><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-110\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\" alt=\"SMCC-english2\" width=\"255\" height=\"126\" \/><\/a><\/p>\n<p>The main cause of Alzheimer\u2019s disease is a dysfunctional protein according to a study of over 3,600 post-mortem brains. It was previously unknown if damaged or dysfunctional protein known as tau or amyloid build-up was the main cause of Alzheimer\u2019s disease.<\/p>\n<p>A research team behind the new study believes that tau is Alzheimer\u2019s primary cause. Tau and amyloid are both proteins found naturally in the body. Tau proteins helps stabilize parts of cells, while amyloid is an abnormal protein created by bone marrow.<\/p>\n<p>The researchers found that damaged tau disrupts the transport ability of neurons eventually leading to their death.<\/p>\n<p><span style=\"text-decoration: underline;\"><a href=\"http:\/\/brain.oxfordjournals.org\/content\/early\/2015\/03\/20\/brain.awv050\" target=\"_blank\">Original research paper<\/a><\/span>\u00a0published in <em>Brain\u00a0<\/em>on\u00a0<strong>March 24<\/strong><span class=\"aBn\" tabindex=\"0\" data-term=\"goog_453723367\"><span class=\"aQJ\"><strong>, 2015<\/strong>.<\/span><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><em><strong>Names and affiliations of selected\u00a0authors<\/strong><\/em><\/span><\/p>\n<h4>Dr. Melissa E. Murray, Mayo Clinic, Neuropathology Laboratory,Florida, U.S.A.<\/h4>\n","protected":false},"excerpt":{"rendered":"<p>The main cause of Alzheimer\u2019s disease is a dysfunctional protein according to a study of over 3,600 post-mortem brains. It was previously unknown if damaged or dysfunctional protein known as tau or amyloid build-up was the main cause of Alzheimer\u2019s disease. A research team behind the new study believes that tau is Alzheimer\u2019s primary cause. [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[2409,992,51],"class_list":["post-4019","post","type-post","status-publish","format-standard","hentry","category-paper-of-interest","tag-alzheimers","tag-brain","tag-health"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-12P","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/4019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=4019"}],"version-history":[{"count":1,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/4019\/revisions"}],"predecessor-version":[{"id":4020,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/4019\/revisions\/4020"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=4019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=4019"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=4019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}