{"id":3847,"date":"2015-02-02T17:02:02","date_gmt":"2015-02-02T22:02:02","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=3847"},"modified":"2015-02-02T11:57:10","modified_gmt":"2015-02-02T16:57:10","slug":"gene-causing-common-scoliosis-identified","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/gene-causing-common-scoliosis-identified\/","title":{"rendered":"Gene causing common scoliosis identified<img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<div id=\"attachment_3848\" style=\"width: 207px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2015\/02\/5509928741_7ee89af75e_z.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-3848\" class=\"size-medium wp-image-3848\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2015\/02\/5509928741_7ee89af75e_z-197x300.jpg\" alt=\"Idiopathic scoliosis is a medical condition by lateral curvature of the spin and a rotation of the vertebral bodies. (Photo credit: Kfergos, flickr.com)\" width=\"197\" height=\"300\" srcset=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2015\/02\/5509928741_7ee89af75e_z-197x300.jpg 197w, http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2015\/02\/5509928741_7ee89af75e_z.jpg 406w\" sizes=\"auto, (max-width: 197px) 100vw, 197px\" \/><\/a><p id=\"caption-attachment-3848\" class=\"wp-caption-text\">Idiopathic scoliosis is a medical condition by lateral curvature of the spin and a rotation of the vertebral bodies. (Photo credit: <a href=\"https:\/\/www.flickr.com\/photos\/kfergos\/5509928741\/in\/photolist-9oTPRp-ubmFZ-fPfp3u-fPfpe7-fNXR2D-9X7tNB-fPfoJS-fhiMZz-fhy2Zs-dSvdww-dSoVdz-dSoUMZ-bpMWjK-BxfXa-wdzmV-63xsgN-tRrSX-fhy2XS-dSusiE-63td8g-fhy37q-fhiN6V-fhy31J-fhiN4D-fhiN3a-63xrNo-4CNLx4-63tdBn-dSpzJr-dSoNgz-dSv8FS-dSv6Qm-dSpzFi-dSv9xq-7Knok9-dSvbf1-8Gy39d-4CNLy4-4DY5D8-noTXM2-5Sz1Fv-4UhNq1-ccyUH-64UX9o-DXch2-6mn3xj-iKfwE-63xrkf-63tcF6-63tcqX\">Kfergos, flickr.com<\/a>)<\/p><\/div>\n<p dir=\"ltr\">Researchers have identified the first gene causing idiopathic scoliosis, the most common type of spinal deformity. They identified 11 family members of a French family that were carriers of a rare variant of the gene, called POC5, and then used zebrafish to confirm that this variant really cause spinal deformity.<\/p>\n<p dir=\"ltr\">This study is the first step in understanding and perhaps preventing idiopathic scoliosis.<\/p>\n<p dir=\"ltr\">Videos are available <span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.youtube.com\/watch?v=MgAUEuhWx3Q\" target=\"_blank\">here<\/a><\/span>.<\/p>\n<p><span style=\"text-decoration: underline;\">Original research paper<\/span>\u00a0published in <em>The Journal of Clinical Investigation\u00a0<\/em>on\u00a0<strong>February 2<\/strong><span class=\"aBn\" tabindex=\"0\" data-term=\"goog_453723367\"><span class=\"aQJ\"><strong>, 2015<\/strong>.<\/span><\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><em><strong>Names and affiliations of selected\u00a0authors<\/strong><\/em><\/span><\/p>\n<h4><a href=\"http:\/\/www.medent.umontreal.ca\/fr\/faculte\/prof\/florina.moldovan\/index.htm\" target=\"_blank\">Florina Moldovan<\/a>, University of Montr\u00e9al,\u00a0Quebec<\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have identified the first gene causing idiopathic scoliosis, the most common type of spinal deformity. They identified 11 family members of a French family that were carriers of a rare variant of the gene, called POC5, and then used zebrafish to confirm that this variant really cause spinal deformity. This study is the first [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3848,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[1274,909,51,53,849],"class_list":["post-3847","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-paper-of-interest","tag-dna","tag-genetics","tag-health","tag-medicine","tag-quebec-en"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2015\/02\/5509928741_7ee89af75e_z.jpg","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-103","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/3847","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=3847"}],"version-history":[{"count":1,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/3847\/revisions"}],"predecessor-version":[{"id":3849,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/3847\/revisions\/3849"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/3848"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=3847"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=3847"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=3847"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}