{"id":2822,"date":"2014-08-21T14:02:11","date_gmt":"2014-08-21T19:02:11","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=2822"},"modified":"2014-08-22T15:49:57","modified_gmt":"2014-08-22T20:49:57","slug":"mers-cov-marmosets-get-sick-like-humans","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/mers-cov-marmosets-get-sick-like-humans\/","title":{"rendered":"MERS-CoV: Marmosets get sick like humans<img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<p><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-110\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\" alt=\"SMCC-english2\" width=\"255\" height=\"126\" \/><\/a><\/p>\n<p><span style=\"color: #000000;\">Researchers have found that marmosets could be used as an animal model to study the Middle East Respiratory Syndrome coronavirus, also known as MERS-CoV. They observed that marmosets carry the same variant of a cell surface protein (DPP4) that MERS-CoV uses to invade human cells. <\/span><\/p>\n<p><span style=\"color: #000000;\">This means that marmosets infected by MERS-CoV get as sick as humans; by contrast, other common animal models such as mice, ferrets and hamsters carry a different DPP4 protein that seems to be resistant to the virus. <\/span><\/p>\n<p><span style=\"color: #000000;\">MERS-CoV was first reported in 2012, causing fever, cough, and can lead to death. No treatment currently exists, but the availability of the marmoset model could help researchers develop countermeasures against it.<\/span><\/p>\n<p><a href=\"http:\/\/www.plospathogens.org\/article\/info%3Adoi%2F10.1371%2Fjournal.ppat.1004250\" target=\"_blank\"><span style=\"text-decoration: underline;\">Original research paper<\/span><\/a>\u00a0published in\u00a0<em>PLOS Pathogens\u00a0<\/em>on\u00a0<strong>August 21, 2014<\/strong>.<\/p>\n<p><span style=\"text-decoration: underline;\"><em><strong>Names and affiliations of selected\u00a0authors<\/strong><\/em><\/span><\/p>\n<h4><a href=\"http:\/\/www.niaid.nih.gov\/labsandresources\/labs\/aboutlabs\/lv\/Pages\/default.aspx\" target=\"_blank\">Heinz Feldmann<\/a><span style=\"color: #000000;\">, National Institute of Allergy and Infectious Diseases; University of Manitoba, Manitoba<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have found that marmosets could be used as an animal model to study the Middle East Respiratory Syndrome coronavirus, also known as MERS-CoV. They observed that marmosets carry the same variant of a cell surface protein (DPP4) that MERS-CoV uses to invade human cells. This means that marmosets infected by MERS-CoV get as sick [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[170,2134,51,53,476],"class_list":["post-2822","post","type-post","status-publish","format-standard","hentry","category-paper-of-interest","tag-biodiversity","tag-disease","tag-health","tag-medicine","tag-public-health"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-Jw","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=2822"}],"version-history":[{"count":3,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2822\/revisions"}],"predecessor-version":[{"id":2852,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2822\/revisions\/2852"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=2822"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=2822"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=2822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}