{"id":2694,"date":"2014-08-06T17:02:49","date_gmt":"2014-08-06T22:02:49","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=2694"},"modified":"2014-08-06T11:30:41","modified_gmt":"2014-08-06T16:30:41","slug":"quantifying-breast-cancer-risk-to-due-gene-mutation","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/quantifying-breast-cancer-risk-to-due-gene-mutation\/","title":{"rendered":"Quantifying breast cancer risk to due gene mutation<img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<p><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-110\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2013\/12\/SMCC-english2.jpg\" alt=\"SMCC-english2\" width=\"255\" height=\"126\" \/><\/a><\/p>\n<p><span style=\"color: #000000;\">Researchers have accurately quantified the risk of breast cancer due to a mutation of a known gene linked to the disease. The study tracked 362 people from families known to carry mutation of a gene called PALB2 which has been linked to breast cancer. <\/span><\/p>\n<p><span style=\"color: #000000;\">Researches\u00a0found that among those younger than 40, the risk of breast cancer was eight to nine times higher than in the general population. The risk was six to eight times higher among those 40 to 60 years of age, and five times as high among those older than 60 years of age. <\/span><\/p>\n<p><span style=\"color: #000000;\">The gene in this study is related to the infamous BRCA genes for which mutation carriers now sometimes choose preventive mastectomies to reduce the risk of getting breast cancer.<\/span><\/p>\n<p><span style=\"text-decoration: underline;\">Original research paper<\/span>\u00a0published in\u00a0<em>The New England Journal of Medicine\u00a0<\/em>on\u00a0<strong>August 6, 2014<\/strong>.<\/p>\n<p><em><span style=\"text-decoration: underline;\"><strong>Names and affiliations of selected\u00a0authors<\/strong><\/span><\/em><\/p>\n<h4><a href=\"http:\/\/www.mcgill.ca\/translational-research-cancer\/researcher-biographies\/foulkes\" target=\"_blank\">William Foulkes<\/a><span style=\"color: #000000;\">, McGill University, Quebec<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have accurately quantified the risk of breast cancer due to a mutation of a known gene linked to the disease. The study tracked 362 people from families known to carry mutation of a gene called PALB2 which has been linked to breast cancer. Researches\u00a0found that among those younger than 40, the risk of breast [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[2092,49,909,51,53,476,849],"class_list":["post-2694","post","type-post","status-publish","format-standard","hentry","category-paper-of-interest","tag-breast-cancer","tag-cancer","tag-genetics","tag-health","tag-medicine","tag-public-health","tag-quebec-en"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-Hs","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2694","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=2694"}],"version-history":[{"count":2,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2694\/revisions"}],"predecessor-version":[{"id":2706,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2694\/revisions\/2706"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=2694"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=2694"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=2694"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}