{"id":2124,"date":"2014-06-25T14:46:39","date_gmt":"2014-06-25T19:46:39","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=2124"},"modified":"2014-06-25T14:47:15","modified_gmt":"2014-06-25T19:47:15","slug":"fungal-extract-could-combat-drug-resistant-bacteria","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/fungal-extract-could-combat-drug-resistant-bacteria\/","title":{"rendered":"Fungal extract could combat drug-resistant bacteria<img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<div id=\"attachment_2117\" style=\"width: 410px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/06\/Untitled-1.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2117\" class=\"size-full wp-image-2117\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/06\/Untitled-1.png\" alt=\"A mold from the Aspergillus family (top) produces a compound called aspergillomarasmine A (bottom) that could help in the fight against antibiotic-resistant bacteria. (Photo credit: Andrew King. Diagram: Gerry Wright)\" width=\"400\" height=\"420\" srcset=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/06\/Untitled-1.png 400w, http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/06\/Untitled-1-285x300.png 285w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/a><p id=\"caption-attachment-2117\" class=\"wp-caption-text\">A mold from the Aspergillus family (top) produces a compound called aspergillomarasmine A (bottom) that could help in the fight against antibiotic-resistant bacteria. (Photo credit: Andrew King. Diagram: Gerry Wright)<\/p><\/div>\n<p><span style=\"color: #000000;\">A chemical extracted from a fungus could help maintain the effectiveness of key antibiotics.<\/span><\/p>\n<p><span style=\"color: #000000;\">In a new study, a fungal extract called aspergillomarasmine A was shown to inhibit NDM-1 and restore the effectiveness of carbapenems against certain bacteria in lab studies.<\/span><\/p>\n<p><span style=\"color: #000000;\">Carbapenems are considered to be \u2018antibiotics of last resort\u2019 for many infections due to the fact that relatively few bacteria have evolved resistance to them. Yet in recent years, some \u2018superbugs\u2019 have evolved an enzyme &#8211; known as NDM-1 &#8211; capable of destroying the carbapenems before the drugs kill them; this makes the infections virtually unstoppable.<\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><a href=\"http:\/\/www.nature.com\/nature\/journal\/v510\/n7506\/full\/nature13445.html\" target=\"_blank\">Original research paper<\/a><\/span>\u00a0published in the journal\u00a0<em>Nature\u00a0<\/em>on\u00a0<strong>June 25, 2014<\/strong>.<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>Names and affiliations of selected\u00a0authors<\/strong><\/span><\/p>\n<h4><span style=\"color: #000000;\"> Gerard D. Wright, McMaster University, Ontario<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>A chemical extracted from a fungus could help maintain the effectiveness of key antibiotics. In a new study, a fungal extract called aspergillomarasmine A was shown to inhibit NDM-1 and restore the effectiveness of carbapenems against certain bacteria in lab studies. Carbapenems are considered to be \u2018antibiotics of last resort\u2019 for many infections due to [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":2117,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[1834,1544,1328,51,53,50,476],"class_list":["post-2124","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-paper-of-interest","tag-antibiotics","tag-bacteria","tag-fungus","tag-health","tag-medicine","tag-ontario","tag-public-health"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/06\/Untitled-1.png","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-yg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=2124"}],"version-history":[{"count":2,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2124\/revisions"}],"predecessor-version":[{"id":2127,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/2124\/revisions\/2127"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/2117"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=2124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=2124"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=2124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}