{"id":1761,"date":"2014-05-29T17:07:21","date_gmt":"2014-05-29T22:07:21","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=1761"},"modified":"2014-06-03T13:28:47","modified_gmt":"2014-06-03T18:28:47","slug":"small-compound-could-help-fight-coronaviruses","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/small-compound-could-help-fight-coronaviruses\/","title":{"rendered":"Small compound could help fight coronaviruses"},"content":{"rendered":"<div id=\"attachment_1741\" style=\"width: 287px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1741\" class=\"size-full wp-image-1741\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d.png\" alt=\"Coronaviruses steal and reshape the internal membranes of their host cells in order to replicate; this microscope image shows what these reshaped membranes look like. (Credit: Volker Thiel, Edward Trybala, and colleagues)\" width=\"277\" height=\"277\" srcset=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d.png 277w, http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d-150x150.png 150w, http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d-268x268.png 268w\" sizes=\"auto, (max-width: 277px) 100vw, 277px\" \/><\/a><p id=\"caption-attachment-1741\" class=\"wp-caption-text\">Coronaviruses steal and reshape the internal membranes of their host cells in order to replicate; this microscope image shows what these reshaped membranes look like. (Credit: Volker Thiel, Edward Trybala, and colleagues)<\/p><\/div>\n<p><span style=\"color: #000000;\">Researchers have found that a small chemical compound called K22 can interfere with the ability of coronaviruses to use the internal membranes of host cells for their own replication. Although it\u2019s still a very long way from being a drug, the fact that the molecule shows activity against a wide range of coronaviruses &#8211; including middle east respiratory syndrome (MERS) &#8211; is of great interest to those studying these viruses.<\/span><\/p>\n<p><a href=\"http:\/\/www.plospathogens.org\/article\/info%3Adoi%2F10.1371%2Fjournal.ppat.1004166\" target=\"_blank\"><span style=\"text-decoration: underline;\">Original research paper<\/span><\/a>\u00a0published in the the journal\u00a0<em>PLOS Pathogens<\/em>\u00a0on\u00a0<strong>May 29, 2014<\/strong>.<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>Names and affiliations of selected\u00a0authors<\/strong><\/span><\/p>\n<h4><span style=\"color: #000000;\">Edward Trybala, University of Gothenburg, Sweden<\/span><\/h4>\n<h4><span style=\"color: #000000;\">Volker Thiel, University of Berne, Switzerland<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have found that a small chemical compound called K22 can interfere with the ability of coronaviruses to use the internal membranes of host cells for their own replication. Although it\u2019s still a very long way from being a drug, the fact that the molecule shows activity against a wide range of coronaviruses &#8211; including [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1741,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[113,1421,51,53,1418,1660,1654,476,1422],"class_list":["post-1761","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-paper-of-interest","tag-biology","tag-coronavirus","tag-health","tag-medicine","tag-mers","tag-mers-cov-en","tag-microbiology","tag-public-health","tag-virus"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/pngbase64abba8008a166349d.png","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-sp","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1761","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=1761"}],"version-history":[{"count":3,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1761\/revisions"}],"predecessor-version":[{"id":1807,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1761\/revisions\/1807"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/1741"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=1761"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=1761"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=1761"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}