{"id":1631,"date":"2014-05-22T17:52:31","date_gmt":"2014-05-22T22:52:31","guid":{"rendered":"http:\/\/sciencemediacentre.ca\/site\/?p=1631"},"modified":"2014-05-25T18:44:07","modified_gmt":"2014-05-25T23:44:07","slug":"biofilm-busting-protein-could-lead-to-new-antimicrobials","status":"publish","type":"post","link":"http:\/\/sciencemediacentre.ca\/site\/biofilm-busting-protein-could-lead-to-new-antimicrobials\/","title":{"rendered":"Biofilm-busting protein could lead to new antimicrobials<img src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/01\/canada_flag_icon_small.gif\">"},"content":{"rendered":"<div id=\"attachment_1565\" style=\"width: 280px\" class=\"wp-caption aligncenter\"><a href=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/73341.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1565\" class=\"size-full wp-image-1565\" src=\"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/73341.jpg\" alt=\"These flow cell images show that biofilms of Pseudomonas aeruginosa and methicillin-resistant staphylococcus aureus can\u2019t form in the presence of the anti-biofilm small protein 1018. (Credit: C\u00e9sar de la Fuente-N\u00fa\u00f1ez)\" width=\"270\" height=\"262\" \/><\/a><p id=\"caption-attachment-1565\" class=\"wp-caption-text\">These flow cell images show that biofilms of Pseudomonas aeruginosa and methicillin-resistant staphylococcus aureus can\u2019t form in the presence of the anti-biofilm small protein 1018. (Credit: C\u00e9sar de la Fuente-N\u00fa\u00f1ez)<\/p><\/div>\n<p><span style=\"color: #000000;\">Researchers have discovered that a synthetic protein is capable of breaking up the slimy films that harmful bacteria use to stick themselves to human tissues.\u00a0<\/span><span style=\"color: #000000;\">The protein molecule is called \u201c1018\u201d and is modelled after proteins produced by the human immune system. <\/span><\/p>\n<p><span style=\"color: #000000;\">A new study shows the molecule prevented biofilm growth in <\/span><span style=\"font-style: italic; color: #000000;\">E. Coli<\/span><span style=\"color: #000000;\">, <\/span><span style=\"font-style: italic; color: #000000;\">Salmonella<\/span><span style=\"color: #000000;\"> and several other disease-causing organisms. The finding offers a new strategy to combat these infectious bacteria, which are increasingly becoming resistant to antibiotics.<\/span><\/p>\n<p><a href=\"http:\/\/www.plospathogens.org\/article\/info%3Adoi%2F10.1371%2Fjournal.ppat.1004152\" target=\"_blank\"><span style=\"text-decoration: underline;\">Original research paper<\/span><\/a>\u00a0published in the the journal\u00a0<em>PLOS Pathogens\u00a0<\/em>on\u00a0<strong>May 22, 2014<\/strong>.<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>Names and affiliations of selected\u00a0authors<\/strong><\/span><\/p>\n<h4><a style=\"color: #1155cc;\" href=\"http:\/\/cmdr.ubc.ca\/bobh\/bob.html\" target=\"_blank\">Robert E. W. Hancock<\/a><span style=\"color: #000000;\">, University of British Columbia, British Columbia<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have discovered that a synthetic protein is capable of breaking up the slimy films that harmful bacteria use to stick themselves to human tissues.\u00a0The protein molecule is called \u201c1018\u201d and is modelled after proteins produced by the human immune system. A new study shows the molecule prevented biofilm growth in E. Coli, Salmonella and [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1565,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[25],"tags":[1544,125,51,53,1545,476],"class_list":["post-1631","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-paper-of-interest","tag-bacteria","tag-british-columbia","tag-health","tag-medicine","tag-organisms","tag-public-health"],"jetpack_featured_media_url":"http:\/\/sciencemediacentre.ca\/site\/wp-content\/uploads\/2014\/05\/73341.jpg","jetpack_shortlink":"https:\/\/wp.me\/p4DqbN-qj","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/comments?post=1631"}],"version-history":[{"count":5,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1631\/revisions"}],"predecessor-version":[{"id":1713,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/posts\/1631\/revisions\/1713"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media\/1565"}],"wp:attachment":[{"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/media?parent=1631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/categories?post=1631"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sciencemediacentre.ca\/site\/wp-json\/wp\/v2\/tags?post=1631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}