New genetic research could help doctors predict which treatments will work best for a given prostate cancer patient.
Researchers sequenced the RNA – molecules that tell them which genes are being expressed – from tumours in 25 prostate cancer patients. They then cross-referenced the RNA data detailed follow-up information, including reactions to different therapies.
They found lots of variability, but some sequence variations were associated with particular outcomes. If validated, the technique could be used to tailor prostate cancer treatments for maximum effectiveness with individual patients.
Original research paper published in the journal Genome Biology on August 25, 2014.
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