Cell Reports
Published October 23, 2018 11:00 EDT (News release from McMaster University)
By comparing two Salmonella strains – one that causes disease in humans and the other in reptiles – researchers discovered another method bacteria use to evade the human immune system and promote infection. Although the two bacteria share most of their genes, researchers found that disease-causing S. Typhimurium turns off the threadlike swimming structures on its surface once it invades a human host cell. This renders the bacteria difficult for the host immune system to detect and respond.
Corresponding author: Brian Coombes, McMaster University – coombes@mcmaster.ca
