Top: Acute myeloid leukemia cells presenting anomalies in standard growth conditions. Below: Acute myeloid leukemia cells preserving their leukemic cell features following in vitro culture with the two chemical molecules referred to in the study cited.(Credit: Institute for Research in Immunology and Cancer)
Previous attempts to grow leukemia stem cells outside the body have fallen short, as the cells lose their cancer stem cell characteristics. Now, scientists have found a way to grow and maintain ‘healthy’ leukemia cancer stem cells outside of the body. This opens the way to screens for drugs that can block the cells’ ability to grow. This finding was made possible by the Quebec Leukemia.
Original research paper published in the journal Nature Methods on February 23, 2014.
Names and affiliations of selected authors
