A screen capture of the video showing cytotoxic T cells (shown as green and orange in the video) attacking a cancer cell (blue). The video also shows cytotoxic T cells attacking virally infected cells, shown in red. (Video credit: University of Cambridge).

A screen capture of the video showing cytotoxic T cells (shown as green and orange in the video) attacking a cancer cell (blue). The video also shows cytotoxic T cells attacking virally infected cells, shown in red. (Video credit: University of Cambridge).

Researchers have captured video of immune cells hunting and destroying cancer and virally-infected cells. The footage was captured using high-resolution 3D time-lapse multi-colour imaging.

T cells, a type of white-blood cell, can recognize antigens on the surface of certain cancerous and infected cells. The video shows these T cells (seen in orange or green) moving around quickly, then sending out protrusions to scan the surface of nearby cells. If a membrane protrusion detects antigens it will inject cytotoxins, poisonous proteins, into the sick cell.

In the video you can see the sick cells shrink and die before the T cell moves on to find another target.

 

The original research paper the video is from was published in Immunity on May 19, 2015, and is available upon request.

Names and affiliations of selected authors

Alex Ritter, University of Cambridge, United Kingdom