Nearly all cervical cancers are associated with persistent cervical infection from cancer-related human papillomavirus (HPV) strains. Results from a randomized clinical trial of about 19,000 women that compared primary HPV testing alone versus Pap test for cervical screening show that primary HPV testing detects precancerous lesions earlier and more accurately than the Pap test. Moreover, women who were HPV negative were less likely than women screened by Pap tests to have cervical pre-cancer after four years.
JAMA
Published July 03, 2018 (News release from JAMA)

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Corresponding author: Gina Suzanne Ogilvie, BC Women’s Hospital and Health Centre, Vancouver – gina.ogilvie@cw.bc.ca